Medical Equipment Expert Opines on Dermatological Laser Patent Infringement Suit

Patent Expert WitnessThis is a patent infringement case relating to non-invasive laser scar removal process. The primary function at issue is the use of a patch infused with a perfluorodecalin solution. The PFD patch is a perfluorodecalin-infused silicone gel patch that helps reduce laser frost caused by laser-induced microbubbles, allowing for multiple laser passes in a single treatment session. Ultimately, the PFD patch’s purpose is to enable faster scar fading that is safe, and decrease the number of overall treatments needed to achieve complete removal. It was alleged that this proprietary process was stolen by a competing company, which utilized it in it’s own laser scar removal equipment.

Question(s) For Expert Witness

  • 1. Please briefly describe your familiarity and experience working with PFD and related solutions.
  • 2. Are you familiar with the use of PFD and/or lasers in scar removal processes?

Expert Witness Response E-138283

I worked with perflorodecalin (PFD) for much of my PhD at Harvard University as a solvent for the assembly of objects in two and three-dimensions. During this work I investigated its interactions with water, polydimethylsiloxane, and epoxy polymers, and I investigated the solubility of various organic chemicals in PFD. In my current job I investigated the diffusion of chemicals through hydrophobic and hydrophilic polymers. This work is relevant to these patents because PFD will diffuse into skin and many of the concepts that govern diffusion of chemicals in polymers are translatable to the diffusion of PFD into skin. I also briefly investigated how to use perfluoroalkanes as blood substitutes due to the ability of perfluoroalkanes to deliver large amounts of oxygen. I have also investigated the delivery of drugs and small chemicals through the bloodstream into cells so I am familiar with the transport of chemicals through living tissues.


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